Are you looking to scale-up or optimize the production of your protein in E. coli?
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Drawing on our experience on hundreds of projects, our team offers expert guidance to define a relevant strategy for an efficient expression of your protein in E. coli.
The team at GTP has successfully produced hundreds of challenging proteins and developed efficient processes for cytoplasmic, periplasmic and soluble or insoluble expression of proteins in E. coli.
Whether your project aims to develop a therapeutic or vaccine protein, to obtain material for research studies or to develop a diagnostic tool, we always consider E. coli to be an excellent first choice – except when expressing complex proteins that require post-translational modifications.
We have the expertise and capabilities to manage complete E. coli production projects from gene synthesis through to milligram to decagram-scale batch production.
Our custom services include:
Our experts have developed advanced tools for enhanced expression of your protein in E. coli.
When gene synthesis is required, we use our own gene optimisation program. This tool takes into account parameters that we consider critical for improved protein expression in E. coli that are usually left aside by gene synthesis companies (see our blog article “How to make gene optimisation for expression in Escherichia coli a piece of cake”).
We also offer four IP-free vectors with different features, all designed to improve protein expression and stability.