Protein expression in P. pastoris

GTP offers customised recombinant protein production services in Pichia pastoris.

Our team has successfully produced a variety of proteins including enzymes, cytokines and antibody fragments using the Pichia pastoris expression system.

Expertise with a range of P. pastoris expression systems

Microbial protein expression services

P. pastoris (now renamed Komagataella phaffii) is a highly competitive host  for the production of recombinant proteins.

This FDA approved system, shows a high secretion capacity of heterologous proteins and can be grown to high cell densities, making it one of the most cost-efficient systems for protein production.

Our team has successfully produced a diversity of proteins (enzymes, antibody fragments, antigens…) in different P. pastoris systems, with inducible or constitutive expression.

Customised services for efficient P. pastoris protein expression

Microbial fermentation - recombinant protein production

GTP offers customised services that span the entire range from gene or sequence to highly productive expression strains and processes:

  • Generation of P. pastoris strain, including expression vector design & construction and when relevant screening of strains, promoters, signal sequences
  • Screening of up to several thousand clones to identify high producers
  • Development  of fed-batch fermentations   
  • Development/optimisation of the purification process

GTP has expertise with other protein expression systems

 

 

Are you looking to experts to produce your challenging protein in P. pastoris?

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