Analytical development

GTP provides expert analytical services for proteins and antibodies

We have vast experience in developing a relevant analytical package to support both process development and final product characterisation.

Expert analytical services for proteins and monoclonal antibodies

Protein analytical services

With over 1,400 projects managed in 20 years, we have developed expert knowledge on a diversity of biomolecules, such as enzymes, cytokines, growth factors, monoclonal antibodies, immunocytokines, virus-like particles and peptides.

Our experienced analytical team masters an extensive range of methods to expertly support process development activities and ensure appropriate product characterisation.

Our services include the following activities:

  • Methods transfer: into and from GTP
  • Methods development and qualification
  • Analytical support to process development
  • Non-GMP DS testing for pre-clinical studies
  • Formulation development
  • Stability studies

 

Comprehensive range of analytical methods

proteins and antibodies characterization

For specialised or cutting-edge characterisation methods, we collaborate with expert partners to offer advanced characterisation of your molecule.

  • Electrophoretic techniques: SDS-PAGE, Capillary electrophoresis, icIEF, Western-blot
  • HPLC platforms with multiple detectors
  • Spectrophotometric assays
  • Bioassays
  • Mass spectrometry: intact mass, peptide mapping, glycan profile 
  • Biophysical characterisation: DLS, MALS, Thermal shift assay (Thermofluor®)
  • Microbiology

Integrated services to support your projects from early phases to industrialisation

GTP’s activities cover the full development cycle of your biotherapeutics, from supporting early-stage discovery through small-scale protein production to comprehensive process development services leading to cGMP manufacturing.

 

 

Please, fill in the required fields.
Please fill out the field with the visible characters (of both the text and image below).