Know how

Recombinant protein production for research & POC studies

GTP helps you produce the recombinant protein material needed for your research and proof-of-concept studies and assess the manufacturability of your protein to de-risk the later stages of your project.

Our expert scientists have developed solutions for over 1,200 recombinant protein production projects

Unique expertise in R&D protein production

Recombinant protein development projects generally start with a research-scale production for in vitro and in vivo studies or to assess the developability of the molecule. These feasibility studies are key to the success of a global protein programme. They should be conducted with agility, with a mind that's open to innovation and that fully understands the risks of each option.

The majority of CMOs, whose mission is to manufacture proteins for clinical trials and market supply, are neither willing nor structured appropriately to be competitive for this type of studies. Most academic protein platforms or CROs are able to produce milligram-scale quantities of recombinant proteins, but may lack the overall perspective your project needs. This often leads to a project redesign along the way and extra added costs.

GTP's experts have a vivid scientific interest in both classical and unconventional protein projects. Over the last 15 years, we have acquired vast experience with over 1,200 different  recombinant protein projects. A large number of these projects belonged to the Proof-of-Concept part of a larger development project, in which we were also involved.

Efficient solutions for highly challenging protein production projects 

GTP adds extra value to your early-stage recombinant protein project by offering a unique mix of protein research proficiency and process expertise. Our experience in development, scale-up, validation and transfer will help you understand the challenges ahead from the get-go.

Our organization is structured to successfully handle these small scale recombinant protein productions for research and POC studies: we offer the adequate flexibility, turnaround-time and pricing structure.

For non-Mab proteins, when there is no evidence pointing towards a specific expression system, we conduct comparative feasibility studies thanks to our multi-system capabilities

We combine our experience with hundreds of challenging recombinant proteins with our process development skills to advise on the most suitable and least risky strategy for your project.

 

Research & process Process development for complex proteins 1