Capabilities

Insect cell expression system

GTP has over 15 years of experience in the expression of recombinant proteins in baculovirus-insect cell system. We are confirmed experts in the production of target proteins for research, reagent proteins for diagnostic and analytical assays, and of vaccine proteins using insect cell expression system.

Over 200 successful protein expressions in insect cells with modular capacities to fit all your protein manufacturing needs

Insect cell expression system for timely and cost-effective production

The popularity of the insect cell-baculovirus expression system lies in its ability to produce relatively large quantities of post-translationally modified eukaryotic proteins. Production only takes a relatively short period of time and can be completed at competitive production costs.

Since the system is lytic, it is suited for both intracellular and secreted proteins, and is ideal for protein projects with inhibitory or toxic effects on mammalian host cells.

For this reason, insect cell expression has been largely used for the production of a variety of target proteins. But this lytic feature is a limitation for industrial production, for which mammalian cells are still largely preferred, particularly for therapeutic projects.

Insect cells

Expert services for successful large-scale protein expression in insect cells

For very challenging recombinant proteins, when the potential of insect cells is required and needs to be adapted to large-scale production, GTP offers extensive expertise and capabilities.

To help you on your way to successful production in insect cells, GTP offers a comprehensive range of services including:

  • Generation of recombinant baculovirus and virus stock preparation
  • Production and characterisation of cell and virus banks
  • Optimisation of cell culture critical parameters

Depending on your project's stage of development, your objectives and IP constraints, our expert team will guide you towards the insect cell-baculovirus technologies that best fit your needs and goals.

We also offer process development services for insect cells