Process development

Our expert scientists are focused on developing the best process for your specific molecule.

We offer a unique combination of protein research culture and recognized expertise in process development. Our experts enjoy a good challenge and provide solutions to even the most challenging recombinant protein development projects.

Vast experience with challenging recombinant protein projects 

When contemplating a development programme for an innovative or complex recombinant protein, one of the keys to success is understanding the unique challenge your specific protein presents.

The majority of CMOs and CDMOs who manufacture recombinant proteins for clinical trials and market supply are reluctant to take on process development projects that do not fall under a well-established standard.

Here at GTP, we have a vivid scientific interest in “non-conventional” protein development projects. Over the years, we have developed over 1400 protein projects, covering a wide range of proteins and achieved widespread recognition for our expertise in the development of upstream and downstream processes for challenging proteins.

 

Seamless process transfer to manufacturing

Our unique focus is to develop the best process for your recombinant protein: we adapt the process to the protein, not the other way around.

We have acquired over 19 years of experience in all prominent industrial microbial, mammalian and insect cell expression systems (E. coli, P. pastoris, mammalian and insect cells) and have the necessary agility to customise downstream processes for every specific case.

When established standards are not applicable, we suggest innovative approaches, always with process transferability in mind.

For a cost-effective and seamless transfer to the cGMP manufacturing suite of your choice, we use methods and platforms that are identical to those used by most CMOs.

Downstream development 2 Process development for complex proteins 2